Perhaps the fastest growth area in commercial polymer science is the field of biopolymers. Biopolymers are unique and have provided new opportunities in green engineering, packaging, cosmetic and food industries, and medicine (tissue engineering). GPC/SEC data is critical to monitor the degradation of biopolymers. However, characterization of biopolymers by GPC/SEC is challenging due to the nature of these materials. Typically such polymers carry various active sites with a range of polarities on their molecular chains causing difficulties in obtaining complete recovery through common GPC columns. PolyAnalytik has successfully completed many projects developing multi-detection GPC methods using proprietary polar and non-polar columns. These columns have provided a tremendous edge for complete characterization of popular biopolymers such as Polylactic Acid (PLA), Polyhudroxybutyrate (PHB), Polycaprolactone (PCL), Chitosan, Beta Glucans, Starches and Cellulostic Materials.